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Sunday, May 26, 2013

This coulda been the last chapter of my first real college research paper!

So I did this paper when I was a freshman at Millikin University for my honors english and seminar course, it was one of the first real papers I ever wrote and was the first college paper that one of my college professors actually liked and said I did a good job on and I'm pretty sure she gave me an A for the class and that assignment because of it.  Anyways, the paper was called, well I don't remember exactly for sure what the paper was called, but it was something like 'The Origins of the Irish Republican Army' and pretty much I traced the origin of the IRA and the events of the Easter Rebellion in 1916 all the way back to the Irish Potato Famine in 1845-1852, claiming that this deep seated hatred for Britain had started back then when many Irish potato farmers blamed British landowners and their policies for, if not causing the famine, at least exacerbating it to large proportions.  Even wikipedia says this on their page on the famine when they write 'the impact and human cost in Ireland—where one-third of the population was entirely dependent on the potato for food—was exacerbated by a host of political, ethnic, religious, social and economic factors which remain the subject of historical debate' and later on it says that the famine 'became a rallying cry for nationalist movements,' proving my thesis when I didn't know nothing and was a simple college freshmen getting help from Emily because I didn't know how to write college papers.  Anyways, I saw this the other day, and it brought back memories for me, check it out

Mystery of Irish Potato Famine Solved

The Irish potato famine that caused mass starvation and approximately 1 million deaths in the mid-19th century was triggered by a newly identified strain of potato blight that has been christened "HERB-1," according to a new study.
An international team of molecular biologists studied the historical spread of Phytophthora infestans, a funguslike organism that devastated potato crops and led to the famine in Ireland. The precise strain of the pathogen that caused the devastating outbreak, which lasted from 1845 to 1852, had been unknown.
"We have finally discovered the identity of the exact strain that caused all this havoc," study co-author Hernán Burbano, a researcher at the Max Planck Institute for Developmental Biology in Germany, said in a statement. [Microscopic Worlds Gallery: Fascinating Fungi]
Previously, a Phytophthora strain called US-1 was thought to have triggered the potato famine, but by sequencing the genomes of preserved samples of the plant pathogen, the researchers discovered that a different strain — one that is new to science — was the real culprit.
"Both strains seem to have separated from each other only years before the first major outbreak in Europe," Burbano said.
DNA detectives
The researchers studied 11 historic samples from potato leaves that were collected about 150 years ago in Ireland, the United Kingdom, Europe and North America.
The scientists found these ancient samples, which were preserved at the Botanical State Collection Munich and the Kew Gardens in London, still had many intact pieces of DNA. In fact, the DNA quality was so good the researchers were able to sequence the entire genome of Phytophthora infestans and its host, the potato, within just a few weeks.
"The degree of DNA preservation in the herbarium samples really surprised us," study co-author Johannes Krause, a professor of paleogenetics at the University of Tübingen in Germany, said in a statement.
The decoded genomes of these historical samples were then compared with modern Phytophthora strains from Europe, Africa and the Americas. The results enabled the researchers to trace the evolution of the pathogen, including where and when the HERB-1 and US-1 strains likely diverged.
According to the study, Phytophthora infestans originated in Mexico's Toluca Valley. When Europeans and Americans first came to Mexico in the 16th century, the pathogen experienced increased genetic diversity, and in the early 1800s, the HERB-1 Phytophthora strain emerged and was brought out of Mexico, the researchers said.
By the summer of 1845, the HERB-1 strain had arrived at European ports, and the potato disease spread throughout Ireland and the United Kingdom, causing the Irish potato famine. In the 20th century, as new varieties of potatoes were introduced, the HERB-1 strain was eventually replaced by the US-1 Phytophthora strain, the researchers said.
Evolving blight
This evolutionary change may have been spurred by the introduction of new crop breeding methods, which suggests that breeding techniques may affect the genetic makeup of plant pathogens.
"Perhaps this strain became extinct when the first resistant potato varieties were bred at the beginning of the 20th century," lead author Kentaro Yoshida, a researcher at The Sainsbury Laboratory in the United Kingdom, said in a statement. "What is for certain is that these findings will greatly help us to understand the dynamics of emerging pathogens."
The new study marks the first time scientists have decoded the genome of a plant pathogen and its host from dried herbarium samples.
"Herbaria represent a rich and untapped source from which we can learn a tremendous amount about the historical distribution of plants and their pests — and also about the history of the people who grew these plants," Yoshida said.
Yoshida and his colleagues report their findings in a paper that was submitted May 17 for publication in the journal eLife.